The Science

The science behind why beef organs are the most nutrient-dense food on the planet — and why women need them most.

For thousands of years, organ meats were the most prized food in virtually every traditional culture. Our ancestors instinctively knew what modern science now confirms: gram for gram, beef organs contain more essential vitamins, minerals, and bioactive compounds than any other food source.

Below is a summary of the research supporting each ingredient in Truly Fem.

🟤 Beef Liver — Nature's Multivitamin

Beef liver is the single most nutrient-dense food known to science. A 100g serving provides:

• Vitamin A (retinol): 16,899 IU — over 300% of the daily value. Essential for skin health, immune function, and reproductive health. Unlike beta-carotene from plants, retinol from liver is immediately bioavailable.
  Source: USDA FoodData Central; Tanumihardjo SA. Vitamin A: biomarkers of nutrition for development. Am J Clin Nutr. 2011.
• Vitamin B12: 59.3 µg — nearly 1,000% of the daily value. Critical for energy production, nervous system function, and red blood cell formation. B12 deficiency is common in women and linked to fatigue and brain fog.
  Source: O'Leary F, Samman S. Vitamin B12 in health and disease. Nutrients. 2010;2(3):299-316.
• Folate: 290 µg — essential for DNA synthesis and critical during reproductive years.
  Source: Bailey LB, Gregory JF. Folate metabolism and requirements. J Nutr. 1999;129(4):779-782.
• Iron (heme): 6.5 mg of highly bioavailable heme iron — absorbed 2-3x more efficiently than plant-based iron. Iron deficiency is the most common nutritional deficiency in women worldwide.
  Source: Hurrell R, Egli I. Iron bioavailability and dietary reference values. Am J Clin Nutr. 2010;91(5):1461S-1467S.
• Copper: 9.8 mg — supports energy metabolism and collagen production for skin elasticity.

🫀 Beef Heart — The Energy Powerhouse

Beef heart is the richest natural source of Coenzyme Q10 (CoQ10), a compound essential for cellular energy production.

• CoQ10: Found in the mitochondria of every cell, CoQ10 is essential for producing ATP — the body's energy currency. Natural CoQ10 levels decline with age, particularly after 30. Studies show CoQ10 supplementation can reduce fatigue, support cardiovascular health, and improve exercise performance.
  Source: Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10. Mol Biotechnol. 2007;37(1):31-37.
• B Vitamins (B2, B6, B12): Supports energy metabolism and mood regulation.
• Iron and Zinc: Essential minerals for immune function and hormone production.
• Collagen and Elastin: Supports skin, joint, and connective tissue health.

🫘 Beef Kidney — Detox & Immune Support

• Selenium: 141 µg per 100g — over 250% of the daily value. Selenium is critical for thyroid function, immune response, and antioxidant defense. The thyroid contains more selenium per gram than any other organ in the body.
  Source: Rayman MP. Selenium and human health. Lancet. 2012;379(9822):1256-1268.
• Vitamin B12: 28.2 µg — supporting energy and neurological function.
• DAO (Diamine Oxidase): A naturally occurring enzyme that helps break down histamine. Relevant for women with histamine intolerance, which can worsen during hormonal fluctuations.
  Source: Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007;85(5):1185-1196.

🌸 Bovine Ovary — Hormonal Balance Support

Bovine ovary supplementation is rooted in the principle of glandular therapy — the concept that consuming a specific organ provides targeted nutritional support to the corresponding organ in the body.

• Ovary-specific peptides and growth factors: Contain tissue-specific nutrients that may support the body's own hormonal production and balance.
• Traditional use: Bovine glandular therapy has been used in functional medicine for decades. Dr. Royal Lee pioneered this approach in the 1920s, and it remains a cornerstone of naturopathic and integrative medicine.
  Source: Harrower HR. Practical Organotherapy: The Internal Secretions in General Practice. 1922.
• Hormonal precursors: May provide building blocks for the body's natural hormone production, particularly relevant during perimenopause and menopause when ovarian function declines.

🌺 Bovine Uterus — Female Wellness Support

• Uterine-specific peptides: Provides tissue-specific nutrients that support uterine health and function.
• Like supports like: Based on the glandular therapy principle that consuming uterine tissue provides the raw materials for the body to maintain and repair its own uterine tissue.
• Traditional use: Used historically across cultures to support women through menstruation, fertility, and menopause.

🌷 Bovine Fallopian Tubes — Complete Reproductive Support

• Complements the ovary and uterus blend to provide comprehensive reproductive system support.
• Contains unique peptides and nutrients specific to fallopian tube tissue.
• Together with bovine ovary and uterus, creates a complete female reproductive support matrix not found in any other supplement on the market.

Why whole-food organs beat synthetic supplements

The nutrients in beef organs exist in their natural matrix — surrounded by cofactors, enzymes, and peptides that enhance absorption. This is why organ-derived nutrients are significantly more bioavailable than their synthetic counterparts:

• Heme iron from organs is absorbed at 15-35%, vs. non-heme iron from supplements at 2-20%
  Source: Hurrell R, Egli I. Am J Clin Nutr. 2010.
• Retinol (vitamin A) from liver is immediately usable, while beta-carotene from plants requires conversion — a process that is genetically inefficient in up to 45% of the population
  Source: Leung WC et al. Two common single nucleotide polymorphisms in the gene encoding beta-carotene 15,15'-monoxygenase alter beta-carotene metabolism. FASEB J. 2009.
• B12 from organs is in its natural methylcobalamin and adenosylcobalamin forms, vs. the synthetic cyanocobalamin found in most supplements
• CoQ10 from heart is in its natural ubiquinol form, which is more readily absorbed than synthetic ubiquinone

Why women need organ nutrition more than men

Women have unique nutritional demands that organ meats are uniquely positioned to address:

• Iron: Women lose iron monthly through menstruation. Up to 30% of women worldwide are iron deficient. Heme iron from organs is the most efficient way to replenish stores.
  Source: WHO. Worldwide prevalence of anaemia 1993-2005.
• Folate: Critical for women of reproductive age. Organ meats provide natural folate (not synthetic folic acid), which is important for the estimated 40% of women with MTHFR gene variants.
  Source: Crider KS et al. MTHFR 677C→T genotype is associated with folate and homocysteine concentrations. J Nutr. 2011.
• B12: Women are more likely to be B12 deficient than men, especially those on plant-heavy diets. Deficiency symptoms include fatigue, brain fog, and mood disorders.
• Selenium: Essential for thyroid function — and thyroid disorders affect women 5-8x more often than men.
  Source: Hollowell JG et al. Serum TSH, T4, and thyroid antibodies in the United States population. J Clin Endocrinol Metab. 2002.

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The information provided is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting any new supplement.

Ready to nourish your body the way nature intended?